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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|PALB2 L947S||osteosarcoma||sensitive||PARP Inhibitor (Pan)||Olaparib||Preclinical - Cell culture||Actionable||In a preclinical study, osteosarcoma cells expressing PALB2 L947S were sensitive to treatment with Lynparza (olaparib), demonstrating decreased cell growth in culture (PMID: 31586400).||31586400|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|