Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Profile Name | ROS1 fusion ROS1 F2004V |
Gene Variant Detail | |
Relevant Treatment Approaches |
Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|---|
ROS1 fusion ROS1 F2004V | Advanced Solid Tumor | predicted - sensitive | NUV-520 | Preclinical - Cell culture | Actionable | In a preclinical study, NUV-520 treatment inhibited viability of cells expressing ROS1 F2004V in the context of a ROS1 fusion in culture (Cancer Res 2022;82(12_Suppl):Abstract nr 3336). | detail... |