Molecular Profile Detail


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Profile Name ATM Q1331H ATM I1441fs
Gene Variant Detail

ATM I1441fs (loss of function - predicted)

ATM Q1331H (unknown)

Relevant Treatment Approaches


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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
ATM Q1331H ATM I1441fs lung non-small cell carcinoma predicted - sensitive Radiotherapy Case Reports/Case Series Actionable In a retrospective analysis, radiotherapy treatment resulted in 3.1 months of local disease control and no in-field recurrence in a patient with non-small cell lung cancer harboring ATM I1441fs and Q1331H (PMID: 28055970). 28055970