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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|KMT2A rearrange||acute myeloid leukemia||not applicable||N/A||Clinical Study||Prognostic||In multiple clinical studies, KMT2A rearrangements, specifically partial tandem duplications, were associated with a poor overall survival in acute myeloid leukemia patients (PMID: 24487413, PMID: 22915647, PMID: 22417203, PMID: 21881046).||21881046 24487413 22417203 22915647|
|KMT2A rearrange||acute myeloid leukemia||not applicable||N/A||Guideline||Prognostic||KMT2A rearrangements (t(v;11q23.3)) are associated with a poor/adverse prognosis in patients with non-APL acute myeloid leukemia (NCCN.org).||detail...|
|PubMed Id||Reference Title||Details|
|(22915647)||A novel hierarchical prognostic model of AML solely based on molecular mutations.||Full reference...|
|(21881046)||Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia.||Full reference...|
|(24487413)||Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients.||Full reference...|
|(22417203)||Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.||Full reference...|