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|Therapy Name||Carboplatin + Idronoxil|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Carboplatin||Paraplatin||CBDCA||Chemotherapy - Platinum 7||Paraplatin (carboplatin) is a second-generation platinum compound and is activated intracellularly to form reactive platinum complexes that cross link DNA with DNA and with proteins. This induces apoptosis and inhibits cell growth (NCI Drug Dictionary).|
|Idronoxil||Phenoxodiol|NV-06|3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol||Idronoxil is an isoflavone analog that leads to decreased Cdk2 activity (PMID: 15833870) and activation of the mitochondrial caspase pathway, and may lead to cell cycle arrest and apoptosis (PMID: 16388521) and decreased proliferation of tumor cells (PMID: 20564423).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|