Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Therapy Name||Megestrol acetate + Pterostilbene|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Megestrol acetate||Megace||MGA|Linmegestrol|Magestin|Megestat|Megeron||Megace (megestrol acetate) is a progestin that activates progesterone receptor signaling and blocks luteinizing hormone signaling, which may lead to potential anti-estrogen and antitumor activities (PMID: 2471590).|
|Pterostilbene||Pterostilbene is a stilbenoid that potentially functions as an antioxidant by preventing cellular damage induced by reactive oxygen species, and may have anti-inflammatory and pro-apoptotic effects (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT03671811||Phase II||Megestrol acetate + Pterostilbene Megestrol acetate||Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy||Recruiting||USA||0|