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Therapy Name | EPZ004777 |
Synonyms | |
Therapy Description |
EPZ004777 is a small molecule that inhibits DOT1L, which results in decreased histone H3 lysine 79 dimethylation, and potentially leads to decreased tumor cell proliferation (PMID: 21741596, PMID: 27535106, PMID: 31888761). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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EPZ004777 | EPZ4777|EPZ-004777|EPZ 004777 | DOT1L Inhibitor 3 | EPZ004777 is a small molecule that inhibits DOT1L, which results in decreased histone H3 lysine 79 dimethylation, and potentially leads to decreased tumor cell proliferation (PMID: 21741596, PMID: 27535106, PMID: 31888761). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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