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Therapy Name | XL388 |
Synonyms | |
Therapy Description |
XL388 is a selective ATP-competitive mTOR inhibitor that inhibits mTORC1 and mTORC2, resulting in decreased activation of downstream targets and potentially leading to decreased tumor growth (PMID: 23394126, PMID: 28404914, PMID: 27385099). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
XL388 | XL-388|XL 388 | mTOR Inhibitor 51 | XL388 is a selective ATP-competitive mTOR inhibitor that inhibits mTORC1 and mTORC2, resulting in decreased activation of downstream targets and potentially leading to decreased tumor growth (PMID: 23394126, PMID: 28404914, PMID: 27385099). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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