Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|EC-70124||JAK2 Inhibitor 17||EC-70124 is a multi-kinase inhibitor with activity against IKBKB and JAK2 and demonstrates anti-tumor activity in cell lines and animal models (PMID: 26826115, PMID: 30575954).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||prostate cancer||not applicable||EC-70124||Preclinical - Cell line xenograft||Actionable||In a preclinical study, EC-70124 inhibited proliferation, colony formation, Stat3 activity, and NFkappaB activity in prostate cancer cells and prostate cancer stem cells in culture and inhibited tumor growth in cell line xenografts (PMID: 26826115).||26826115|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|