Therapy Detail

Therapy Name CCT137690 + Radiotherapy
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CCT137690 AURK Inhibitor (Pan) 11 CCT137690 selectively inhibits aurora kinases (AURKA, AURKB, and AURKC) with nanomolar affinities (PMID: 20565112).
Radiotherapy
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable CCT137690 + Radiotherapy Preclinical - Cell culture Actionable In a preclinical study, colorectal cancer cells were more sensitive to radiotherapy when treated with CCT137690 (PMID: 24476310). 24476310
Clinical Trial Phase Therapies Title Recruitment Status