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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SA16||Aurka Inhibitors 24 PDPK1 Inhibitor 10||SA16 is a dual inhibitor of phosphoinositide-dependent kinase-1 (PDPK1) and AURKA, which may result in cell proliferation blockade and induction of apoptosis (PMID: 27797168, PMID: 31683659).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||glioblastoma||not applicable||SA16||Preclinical - Cell culture||Actionable||In a preclinical study, SA16 treatment in glioblastoma cells resulted in decreased cell proliferation, reduced cell viability, and apoptotic induction in culture, and inhibited glioma stem cell formation (PMID: 27797168).||27797168|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|