Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Therapy Name | 9F7-F11 |
Synonyms | |
Therapy Description |
9F7-F11 is a non-ligand competitive antibody targeting ERBB3 (HER3) that has enhanced binding to ERBB3 (HER3) in the presence of its ligand NRG1, which reduces downstream signaling and may inhibit growth of NRG1-expressing tumors (PMID: 28507002). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
9F7-F11 | HER3 (ERBB3) Antibody 23 | 9F7-F11 is a non-ligand competitive antibody targeting ERBB3 (HER3) that has enhanced binding to ERBB3 (HER3) in the presence of its ligand NRG1, which reduces downstream signaling and may inhibit growth of NRG1-expressing tumors (PMID: 28507002). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|