Therapy Detail

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Diphenhydramine Aleryl
Isatuximab Sarclisa SAR650984|isatuximab-irfc CD38 Antibody 15 Sarclisa (isatuximab-irfc) is a humanized monoclonal antibody against CD38 that induces anti-tumor immune reaction against CD38-positive tumor cells (PMID: 24987056). Sarclisa (isatuximab-irfc) in combination with Pomalyst (pomalidomide) and dexamethasone is FDA approved for use in patients with multiple myeloma who have received two or more prior therapies, and in combination with Kyprolis (carfilzomib) and dexamethasone for patients with relapsed or refractory multiple myeloma who have received one to three prior lines of therapy (FDA.gov).
Methylprednisolone Artisone-Wyeth 6alpha-Methylprednisolone
Ranitidine Alquen Ranitidine HCL

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

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  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02960555 Phase II Diphenhydramine + Isatuximab + Methylprednisolone + Ranitidine Trial of Isatuximab (SAR650984) in Patients With High Risk Smoldering Multiple Myeloma Recruiting USA 0


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