Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Therapy Name | R11.1.6 + ZSTK474 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
R11.1.6 | KRAS Inhibitor 17 | R11.1.6 is a protein antagonist that preferentially binds KRAS G12D, potentially resulting in inhibition of downstream Ras signaling (PMID: 28724936, PMID: 29720559). | ||
ZSTK474 | ZSTK-474 | PI3K Inhibitor (Pan) 41 | ZSTK474 is a pan-PI3K inhibitor, which blocks PI3K/AKT signaling to prevent cell growth (PMID: 16622124, PMID: 30205797). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|