Drug Detail


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Drug Name ZSTK474
Trade Name
Synonyms ZSTK-474
Drug Descriptions

ZSTK474 is a pan-PI3K inhibitor, which blocks PI3K/AKT signaling to prevent cell growth (PMID: 16622124, PMID: 30205797).

DrugClasses PI3K Inhibitor (Pan) 40
CAS Registry Number 475110-96-4
NCIT ID C95723


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Therapy Name Drugs Efficacy Evidence Clinical Trials
HQP1351 + ZSTK474 HQP1351 ZSTK474 0 0
Imatinib + ZSTK474 Imatinib ZSTK474 0 0
Nilotinib + ZSTK474 Nilotinib ZSTK474 0 0
PD-0325901 + ZSTK474 PD-0325901 ZSTK474 0 0
R11.1.6 + ZSTK474 R11.1.6 ZSTK474 0 0
Ruxolitinib + ZSTK474 Ruxolitinib ZSTK474 2 0
Selumetinib + ZSTK474 Selumetinib ZSTK474 1 0
Vemurafenib + ZSTK474 Vemurafenib ZSTK474 1 0
ZSTK474 ZSTK474 0 0

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