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NCT ID	NCT06413706
Title	A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy
Recruitment	Not yet recruiting
Gender	both
Phase	Phase II
Variant Requirements	Yes
Sponsors	Eli Lilly and Company
Indications	diffuse glioma, H3 G34 mutant IDH-mutant and 1p/19q-codeleted oligodendroglioma anaplastic oligodendroglioma diffuse midline glioma, H3 K27M-mutant glioblastoma IDH-mutant anaplastic astrocytoma infant-type hemispheric glioma diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype gangliocytoma anaplastic pleomorphic xanthoastrocytoma anaplastic astrocytoma
Therapies	Abemaciclib + Temozolomide Temozolomide
Age Groups:	adult \| child
Covered Countries	USA \| ITA \| FRA \| ESP \| BEL