Disease Detail


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ID DOID:7154
Name anaplastic oligodendroglioma
Definition An oligodendroglioma that is characterized by focal or diffuse malignant morphologic features (prominent nuclear pleomorphism, mitoses, and increased cellularity).
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer cell type cancer high grade glioma oligodendroglioma anaplastic oligodendroglioma


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
BRAF V600E Dabrafenib + Trametinib anaplastic oligodendroglioma sensitive detail...
BRAF V600E Cobimetinib + Vemurafenib anaplastic oligodendroglioma sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05429502 Phase Ib/II Ribociclib + Temozolomide + Topotecan Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors Recruiting USA | ITA | FRA | ESP | DEU | AUS 1
NCT05503797 Phase II Cobicistat + PLX8394 PLX8394 A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations Recruiting USA | ITA | GBR | FRA | ESP | DEU | CAN 2
NCT05698524 Phase I Abexinostat + Temozolomide A Study of Temodar With PCI-24781 for Patients With Recurrent Glioma Recruiting USA 0
NCT05887882 Phase I TGF-beta-imprinted NK cells Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Brain Tumors (PNOC028) Not yet recruiting USA 0
NCT06011109 Phase Ib/II Bevacizumab APG-157 Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab Recruiting USA 0