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ID DOID:3078
Name grade III astrocytoma
Definition An astrocytoma that is characterized by cells with regular, round to oval nuclei.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer nervous system cancer central nervous system cancer astrocytoma grade III astrocytoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
IDH1 R132H Azacitidine grade III astrocytoma sensitive detail...
IDH1 mutant N/A grade III astrocytoma not applicable detail...
IDH2 mutant N/A grade III astrocytoma not applicable detail...
Unknown unknown Trabedersen grade III astrocytoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02052778 Phase Ib/II Futibatinib A Study of TAS-120 in Patients With Advanced Solid Tumors Active, not recruiting USA 9
NCT02800486 Phase II Cetuximab Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA Recruiting USA 0
NCT03128047 Phase I Bevacizumab + Temozolomide HUMC 1612: Optune NovoTTF-200A System Recruiting USA 0
NCT03581292 Phase II Temozolomide + Veliparib Veliparib Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations Recruiting USA | CAN 3
NCT03657576 Phase I C134-HSV-1 Trial of C134 in Patients With Recurrent GBM (C134-HSV-1) Active, not recruiting USA 0
NCT03893487 Phase I CUDC-907 Fimepinostat in Treating Brain Tumors in Children and Young Adults (PNOC016) Recruiting USA 1
NCT03911388 Phase I HSV-1 G207 HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors Recruiting USA 0
NCT04047303 Phase I CC-90010 CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma Recruiting USA 1
NCT04254419 Phase I Intra-tumoral Injection of Natural Killer Cells in High-Grade Gliomas Not yet recruiting USA 0
NCT04295759 Phase I INCB7839 INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas Active, not recruiting USA 0
NCT04482933 Phase II HSV-1 G207 HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma Not yet recruiting USA 0
NCT04541082 Phase I ONC206 Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms Recruiting USA 0
NCT04691960 Phase II Metformin A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging Recruiting USA 0
NCT04704154 Phase II Nivolumab + Regorafenib A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors Recruiting USA 7