Disease Detail

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ID DOID:3078
Name grade III astrocytoma
Definition An astrocytoma that is characterized by cells with regular, round to oval nuclei.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer nervous system cancer central nervous system cancer astrocytoma grade III astrocytoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
IDH1 R132H Azacitidine grade III astrocytoma sensitive detail...
IDH1 mutant N/A grade III astrocytoma not applicable detail...
IDH2 mutant N/A grade III astrocytoma not applicable detail...
Unknown unknown Trabedersen grade III astrocytoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
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NCT03973918 Phase II Binimetinib + Encorafenib Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG (BRAF) Recruiting
NCT04047303 Phase I CC-90010 CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma Recruiting
NCT04254419 Phase I Intra-tumoral Injection of Natural Killer Cells in High-Grade Gliomas Not yet recruiting
NCT04295759 Phase I INCB7839 INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas Recruiting