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ID DOID:3664
Name mast cell neoplasm
Definition A hematologic cancer that has_material_basis_in mast cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer hematologic cancer mast cell neoplasm

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
KIT V560G KIT D816V Quizartinib mast cell neoplasm resistant detail...
KIT D816Y Ripretinib mast cell neoplasm predicted - sensitive detail...
KIT D816Y Avapritinib mast cell neoplasm predicted - sensitive detail...
KIT D816V Avapritinib mast cell neoplasm predicted - sensitive detail...
KIT D816Y Imatinib mast cell neoplasm predicted - resistant detail...
KIT D816Y Sunitinib mast cell neoplasm decreased response detail...
KIT D816Y Regorafenib mast cell neoplasm predicted - resistant detail...
KIT D816Y Midostaurin mast cell neoplasm predicted - sensitive detail...
KIT V560G Ripretinib mast cell neoplasm sensitive detail...
KIT V560G Imatinib mast cell neoplasm sensitive detail...
KIT V560G Sunitinib mast cell neoplasm sensitive detail...
KIT V560G Regorafenib mast cell neoplasm sensitive detail...
KIT V560G Midostaurin mast cell neoplasm sensitive detail...
KIT V560G Avapritinib mast cell neoplasm sensitive detail...
KIT V560G KIT D816V Ripretinib mast cell neoplasm sensitive detail...
KIT V560G KIT D816V Midostaurin mast cell neoplasm sensitive detail...
KIT V560G KIT D816V Avapritinib mast cell neoplasm sensitive detail...
KIT V560G KIT D816V Imatinib mast cell neoplasm resistant detail...
KIT V560G KIT D816V Sunitinib mast cell neoplasm resistant detail...
KIT V560G KIT D816V Regorafenib mast cell neoplasm resistant detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02415608 Phase II Ibrutinib Ibrutinib in Treating Patients With Advanced Systemic Mastocytosis Terminated USA 0
NCT02561988 Phase I Avapritinib (EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies Completed USA | GBR 0