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ID | DOID:4118 |
Name | colon neuroendocrine neoplasm |
Definition | |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation benign neoplasm organ system benign neoplasm gastrointestinal system benign neoplasm intestinal benign neoplasm colonic benign neoplasm colon neuroendocrine neoplasm |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
BRAF V600E | Dabrafenib | colon neuroendocrine neoplasm | predicted - sensitive | detail... |
BRAF V600E | Binimetinib | colon neuroendocrine neoplasm | no benefit | detail... |
BRAF V600E | Cobimetinib + Vemurafenib | colon neuroendocrine neoplasm | predicted - sensitive | detail... |
BRAF V600E | Dabrafenib + Trametinib | colon neuroendocrine neoplasm | predicted - sensitive | detail... |
BRAF V600E | Cetuximab + Encorafenib | colon neuroendocrine neoplasm | predicted - sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT04954820 | Phase II | lutetium Lu 177 dotatate | Assessment of the Schema of Retreatment With Lutathera® in Patients With New Progression of Intestinal Well-differenciated Neuroendocrine Tumor (ReLUTH) | Recruiting | FRA | 0 |
NCT06055439 | Phase Ib/II | CHM-2101 CAR-T cells | A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy | Recruiting | USA | 0 |