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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01089101 Phase Ib/II Selumetinib Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma Active, not recruiting USA 0
NCT02095132 Phase Ib/II Adavosertib + Irinotecan Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors Completed USA | CAN 0
NCT02390843 Phase I Cyclophosphamide + Filgrastim + Simvastatin + Topotecan Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors (AflacST1402) Completed USA 0
NCT02698254 Phase 0 Bevacizumab Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy Active, not recruiting USA 0
NCT03326388 Phase Ib/II Selumetinib Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT) Completed GBR 0
NCT03871257 Phase III Carboplatin + Vincristine Sulfate Selumetinib A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma Recruiting USA | CAN 1
NCT04465643 Phase I Ipilimumab + Nivolumab Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor Recruiting USA 0
NCT06104488 Phase I RO5126766 A Study of Avutometinib for People With Solid Tumor Cancers Recruiting USA 0