Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
CTNNB1 S45F Imatinib desmoid tumor sensitive detail...
CTNNB1 act mut Imatinib desmoid tumor sensitive detail...
CTNNB1 T41A Imatinib desmoid tumor sensitive detail...
Unknown unknown Sorafenib desmoid tumor not applicable detail...
CTNNB1 mutant N/A desmoid tumor not applicable detail...
APC mutant N/A desmoid tumor not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT03785964 Phase III PF-03084014 Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) (DeFi) Active, not recruiting
NCT03886311 Phase II Nivolumab + Talimogene laherparepvec + Trabectedin Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma (TNT) Recruiting