Disease Detail


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
CTNNB1 S45F Imatinib desmoid tumor sensitive detail...
CTNNB1 act mut Imatinib desmoid tumor sensitive detail...
CTNNB1 T41A Imatinib desmoid tumor sensitive detail...
CTNNB1 mutant N/A desmoid tumor not applicable detail...
APC mutant N/A desmoid tumor not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03422679 Phase Ib/II CB-103 Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies Recruiting USA | FRA | ESP | DEU 3
NCT03459469 Phase I BC2059 Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 Active, not recruiting USA | CAN 0
NCT03785964 Phase III Nirogacestat Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) (DeFi) Active, not recruiting USA | ITA | DEU | CAN | BEL 2
NCT03886311 Phase II Nivolumab + Talimogene laherparepvec + Trabectedin Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma (TNT) Recruiting USA 0
NCT04195399 Phase II Nirogacestat A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery Recruiting USA | CAN 2