Disease Detail


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ID DOID:8692
Name myeloid leukemia
Definition A leukemia that is located_in myeloid tissue.
Source DiseaseOntology.org
Alt Ids DOID:8879 DOID:9066 DOID:8910 DOID:8878 DOID:9126
Path disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
CSF1R Y571D Imatinib myeloid leukemia sensitive detail...
JAK2 V617F Imatinib myeloid leukemia resistant detail...
FLT3 exon 14 ins FLT3 N676S A-419259 myeloid leukemia resistant detail...
FLT3 exon 14 ins FLT3 D835Y A-419259 myeloid leukemia resistant detail...
FLT3 exon 14 ins FLT3 F691L A-419259 myeloid leukemia resistant detail...
FLT3 exon 14 ins A-419259 myeloid leukemia sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02129101 Phase I Azacitidine Sonidegib Azacitidine and Sonidegib in Treating Patients With Myeloid Malignancies Completed USA 0
NCT03164057 Phase II Etoposide Filgrastim Dexrazoxane Daunorubicin Idarubicin Fludarabine Asparaginase Cytarabine Sorafenib Mitoxantrone Decitabine Azacitidine A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Recruiting USA 0
NCT03214666 Phase Ib/II GTB-3550 TriKE GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies Terminated USA 0
NCT04260022 Phase I HQP1351 Study of HQP1351 in Subjects With Refractory Chronic Myeloid Leukemia (HQP1351CU101) Recruiting USA 0
NCT04964518 Phase I APG-2575 + Azacitidine A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML) Recruiting USA 2