Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
CSF1R Y571D Imatinib myeloid leukemia sensitive detail...
JAK2 V617F Imatinib myeloid leukemia resistant detail...
PDGFRA N659S Imatinib myeloid leukemia decreased response detail...
PDGFRA Y849S Imatinib myeloid leukemia sensitive detail...
PDGFRA R748G Imatinib myeloid leukemia sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT02129101 Phase I Azacitidine Sonidegib Azacitidine and Sonidegib in Treating Patients With Myeloid Malignancies Active, not recruiting
NCT03164057 Phase II Etoposide Filgrastim dexrazoxane Daunorubicin Idarubicin Fludarabine Asparaginase Cytarabine Sorafenib Mitoxantrone Decitabine Azacitidine A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Recruiting