Disease Detail


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ID DOID:8761
Name acute megakaryocytic leukemia
Definition An acute myeloid leukemia that derives from blood-forming tissue in which megakaryocytes proliferate in the bone marrow and circulate in the blood in large numbers.
Source DiseaseOntology.org
Alt Ids DOID:9009
Path disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia myeloid leukemia acute myeloid leukemia acute megakaryocytic leukemia


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
KIT wild-type Avapritinib acute megakaryocytic leukemia decreased response detail...
JAK2 V617F Ropeginterferon acute megakaryocytic leukemia sensitive detail...
JAK2 V617F AZ960 acute megakaryocytic leukemia sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02530619 Phase I Alisertib Alisertib in Treating Patients With Myelofibrosis or Relapsed or Refractory Acute Megakaryoblastic Leukemia Unknown status USA 0