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Drug Name KN046
Trade Name
Synonyms KN 046|KN-046|Erfonrilimab
Drug Descriptions

KN046 is a bispecific monoclonal antibody that targets PD-L1 (CD274) expressed on tumor cells and CTLA-4 on T lymphocytes, potentially leading to enhanced antitumor immune response (NCI Drug Dictionary).

DrugClasses CTLA4 Antibody 22 Immune Checkpoint Inhibitor 148 PD-L1/PD-1 antibody 93
CAS Registry Number NA
NCIT ID C157632

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + KN046 + Paclitaxel Cisplatin KN046 Paclitaxel 0 0
Gemcitabine + KN046 + Nab-paclitaxel Gemcitabine KN046 Nab-paclitaxel 0 0
KN046 KN046 0 1
KN046 + Lenvatinib KN046 Lenvatinib 0 0


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