Drug Detail


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Drug Name BI-1347
Trade Name
Synonyms BI1347|BI 1347
Drug Descriptions

BI-1347 inhibits CDK8 and CDK19, which leads to reduced levels of phosphorylated Stat1 and increased activity of NK cells, potentially resulting in tumor growth inhibition, in combination with other agents (PMID: 32024684, PMID: 36398965).

DrugClasses CDK8 Inhibitor 5
CAS Registry Number NA


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Therapy Name Drugs Efficacy Evidence Clinical Trials
BI-1347 BI-1347 0 0
BI-1347 + Selumetinib BI-1347 Selumetinib 1 0
BI-1347 + Trametinib BI-1347 Trametinib 1 0

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