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Drug Name RO7425781
Trade Name
Synonyms RO 7425781|RO-7425781|RG6234|RG-6234|RG 6234|Formitamig
Drug Descriptions

RO7425781 (RG6234) is a bispecific antibody that targets GPRC5D expressed on tumor cells and CD3 expressed on T-lymphocytes, potentially resulting in enhanced antitumor immune response and inhibition of tumor growth (Blood (2022) 140 (Supplement 1): 10137-10139, Blood (2022) 140 (Supplement 1): 2091-2092).

DrugClasses CD3 Antibody 92
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carfilzomib + RO7425781 Carfilzomib RO7425781 0 1
Daratumumab + RO7425781 Daratumumab RO7425781 0 1
RO7425781 RO7425781 0 2


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