Drug Detail


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Drug Name Lonafarnib
Trade Name Sarasar
Synonyms SCH66336
Drug Descriptions

Lonafarnib (SCH66336) is a farnesyl transferase inhibitor, which alters post-translational modification and activation of Ras proteins (PMID: 25323927, PMID: 29285232).

DrugClasses Farnesyltransferase Inhibitor 4
CAS Registry Number 193275-84-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Adagrasib + Lonafarnib Adagrasib Lonafarnib 0 0
Docetaxel + Lonafarnib Docetaxel Lonafarnib 0 0
Lonafarnib Lonafarnib 0 0
Lonafarnib + Sotorasib Lonafarnib Sotorasib 0 0
Lonafarnib + Tamoxifen Lonafarnib Tamoxifen 0 0

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