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Drug Name | GSI-18 |
Trade Name | |
Synonyms | |
Drug Descriptions |
GSI-18 is a small molecule compound that binds and inhibits Gamma-secretase inhibiting its activity on downstream targets including NOTCH signaling proteins thus blocking pathway activation in cancer (PMID: 15603957, PMID: 19258443). |
DrugClasses | Gamma secretase inhibitor 13 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GSI-18 | GSI-18 | 0 | 0 |