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Therapy Name | GSI-18 |
Synonyms | |
Therapy Description |
GSI-18 is a small molecule compound that binds and inhibits Gamma-secretase inhibiting its activity on downstream targets including NOTCH signaling proteins thus blocking pathway activation in cancer (PMID: 15603957, PMID: 19258443). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
GSI-18 | Gamma secretase inhibitor 13 | GSI-18 is a small molecule compound that binds and inhibits Gamma-secretase inhibiting its activity on downstream targets including NOTCH signaling proteins thus blocking pathway activation in cancer (PMID: 15603957, PMID: 19258443). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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