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Drug Name | ON044580 |
Trade Name | |
Synonyms | SB17191|ON-044580 |
Drug Descriptions |
ON044580 is a non-ATP competitive inhibitor of BCR-ABL, BCR-ABL (T315I), JAK2, and JAK2(V617F), which may inhibit cell proliferation through inhibition of STAT5 signaling (PMID: 20717479, PMID: 20798787). |
DrugClasses | BCR-ABL Inhibitor 31 JAK2 Inhibitor 17 |
CAS Registry Number | 1253966-44-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ON044580 | ON044580 | 0 | 0 |