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Imgatuzumab (RG7160) is a humanized antibody directed against EGFR, which prevents ligand binding and dimerization, resulting in decreased EGFR signaling and increased immune response toward EGFR-expressing tumor cells (PMID: 23209031, PMID: 28950289).
|DrugClasses||EGFR Antibody 41|
|CAS Registry Number||959963-46-3|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Imgatuzumab + Irinotecan||Imgatuzumab Irinotecan||0||0|