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CBL0137 is a curaxin compound that binds to and inhibits the facilitates chromatin transcription (FACT) complex, resulting in apoptosis in cancer cells (PMID: 25402820) and also disrupts DNA and histone interactions (PMID: 30926878, PMID: 32631516, PMID: 32202904).
|CAS Registry Number||1197996-80-7|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|CBL0137 + Gemcitabine||CBL0137 Gemcitabine||0||0|