Drug Detail


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Drug Name Cofetuzumab pelidotin
Trade Name
Synonyms h6M24-vc0101|PTK7-targeted antibody-drug conjugate|ABBV-647|PF-06647020
Drug Descriptions

Cofetuzumab pelidotin (PF-06647020) is an antibody-drug conjugate comprising a monoclonal antibody against PTK7 linked to Aur0101, which delivers the cytotoxic agent to PTK7-expressing tumor cells, leading to cell death (PMID: 28077676).

CAS Registry Number 1869937-48-3
NCIT ID C123828


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Cofetuzumab pelidotin Avelumab Cofetuzumab pelidotin 0 1
Cofetuzumab pelidotin Cofetuzumab pelidotin 0 2
Cofetuzumab pelidotin + Gedatolisib Cofetuzumab pelidotin Gedatolisib 0 1

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