Drug Detail


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Drug Name CX-072
Trade Name
Synonyms CX072|CX 072|Pacmilimab
Drug Descriptions

CX-072 (Pacmilimab) is a prodrug consisting of a monoclonal antibody to PD-L1 (CD274) and a masking peptide that is cleaved by proteases specific to tumor cells (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3072-3072, PMID: 32681519).

DrugClasses Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 112
CAS Registry Number 2101273-62-3
NCIT ID C132192


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Therapy Name Drugs Efficacy Evidence Clinical Trials
CX-072 CX-072 0 2
CX-072 + CX-2009 CX-072 CX-2009 0 1
CX-072 + Ipilimumab CX-072 Ipilimumab 0 1
CX-072 + Vemurafenib CX-072 Vemurafenib 0 1

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