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Drug Name Denileukin diftitox
Trade Name Ontak
Synonyms DAB389IL2|DAB389-IL2|LY335348|DAB389 interleukin-2
Drug Descriptions

Ontak (denileukin diftitox) is an interleukin-2 (IL-2) recombinant fusion protein comprised of the IL-2 protein and the diptheria toxin, and may potentially inhibit the growth and survival of tumor cells expressing the IL-2 receptor (PMID: 11707818, PMID: 27737881).

CAS Registry Number 173146-27-5


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Denileukin diftitox Denileukin diftitox 0 1
Denileukin diftitox + Sirolimus Denileukin diftitox Sirolimus 0 0
Denileukin diftitox + Temsirolimus Denileukin diftitox Temsirolimus 0 0

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