Drug Detail


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Drug Name H3B-6545
Trade Name
Synonyms SERCA H3B6545|H3B 6545
Drug Descriptions

H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that targets both wild-type and mutant ESR1, which may result in antitumor activity (PMID: 35642432).

DrugClasses Hormone - Anti-estrogens 29
CAS Registry Number 2052130-80-8
NCIT ID C142980


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Therapy Name Drugs Efficacy Evidence Clinical Trials
H3B-6545 H3B-6545 0 1
H3B-6545 + Palbociclib H3B-6545 Palbociclib 0 1

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