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UNC0642 (MP-IN-317) is a histone methyltransferase inhibitor that selectively inhibits EHMT2 (G9A) and EHMT1 (GLP), which may result in decreased methylation and potential cytotoxic effects against cancer cells (PMID: 24102134).
|DrugClasses||EHMT2 Inhibitor 5|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Afatinib + UNC0642||Afatinib UNC0642||0||0|