Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FLT3 A680V||hematologic cancer||sensitive||FLT3 Inhibitor||Gilteritinib||Preclinical - Cell culture||Actionable||In a preclinical study, transformed cells expressing FLT3 A680V were sensitive to treatment with Xospata (gilteritinib) in culture, demonstrating decreased cell viability and decreased Flt3 phosphorylation (PMID: 33563661).||33563661|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|