Molecular Profile Detail


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Profile Name BRAF amp
Gene Variant Detail

BRAF amp (no effect)

Relevant Treatment Approaches


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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF amp lung non-small cell carcinoma not predictive unspecified immune checkpoint inhibitor Clinical Study Actionable In a retrospective clinical study, no significant difference in overall survival (19.0 vs 18.4 months) was found in patients with non-small cell lung cancer harboring BRAF V600E (n=14), amplification (n=5), or non-V600E mutations (n=12) who received immunotherapy compared to those who never received immunotherapy (PMID: 31367539). 31367539