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|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|ALK rearrange ALK V1180L ALK L1196M ALK G1202R||lung non-small cell carcinoma||predicted - resistant||Brigatinib||Case Reports/Case Series||Actionable||In a clinical case study, ALK G1202R and ALK L1196M were identified at disease progression while on Alunbrig (brigatinib) treatment in liquid biopsy of a patient with ALK-positive non-small cell lung cancer also harboring an ALK V1180L (PMID: 29935304).||29935304|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|