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Molecular Profile | RAD51C T132P |
Therapy | Olaparib |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
RAD51C T132P | Advanced Solid Tumor | sensitive | Olaparib | Preclinical - Cell culture | Actionable | In a preclinical study, Lynparza (olaparib) treatment resulted in decreased survival of cells expressing RAD51C T132P in culture (PMID: 33832919). | 33832919 |
PubMed Id | Reference Title | Details |
---|---|---|
(33832919) | Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation. | Full reference... |