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Therapy Name | L-685458 |
Synonyms | |
Therapy Description |
L-685458 is a small molecule which selectively binds and inhibits gamma-secretase inhibiting proteolytic cleavage of downstream targets including NOTCH receptor proteins thus blocking pathway activation in cancer (PMID: 10913280). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
L-685458 | L-685,458 | Gamma secretase inhibitor 13 | L-685458 is a small molecule which selectively binds and inhibits gamma-secretase inhibiting proteolytic cleavage of downstream targets including NOTCH receptor proteins thus blocking pathway activation in cancer (PMID: 10913280). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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