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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Ro 31-8220||Ro-31-8220|Ro 318220||GSK-3beta Inhibitor 4 PKC Inhibitor (Pan) 10||Ro 31-8220 is a pan-protein kinase C (PKC) inhibitor, with additional activity against additional kinases including GSK3-beta, which may increase apoptosis and decrease growth of tumor cells (PMID: 8373348, PMID: 10998351, PMID: 18281471).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||lung non-small cell carcinoma||not applicable||Ro 31-8220||Preclinical - Cell culture||Actionable||In a preclinical study, Ro 31-8220 decreased CREB signaling, and induced apoptosis and inhibited growth of non-small cell lung cancer cells in culture (PMID: 18281471).||18281471|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|