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Therapy Name | Palbociclib + RAD140 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Palbociclib | Ibrance | PD0332991|PD-0332991 | CDK4/6 Inhibitor 13 | Ibrance (palbociclib) is a selective inhibitor of cyclin-dependent kinase 4 (CDK4) and 6 (CDK6) (PMID: 19874578). Ibrance (palbociclib) is approved in combination with an aromatase inhibitor in postmenopausal patients with ER-positive, ERBB2 (HER2)-negative metastatic breast cancer, and in combination with Faslodex (fulvestrant) in patients with ER-positive, ERBB2 (HER2)-negative metastatic breast cancer (FDA.gov). |
RAD140 | RAD-140|RAD 140|EP0062|EP 0062|EP-0062|Vosilasarm | Hormone - Anti-androgens 53 | RAD140 is a selective androgen receptor modulator that results in AR agonist activity, which potentially leads to the regulation of AR target genes, repression of Esr1, and inhibition of tumor growth (PMID: 28974548). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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