Disease Detail


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Name uterine cancer
Definition A female reproductive organ cancer that is located_in the uterus.
Source DiseaseOntology.org
Alt Ids DOID:4363
Path disease disease of cellular proliferation cancer organ system cancer reproductive organ cancer female reproductive organ cancer uterine cancer


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
PTEN mutant GSK2256098 uterine cancer sensitive detail...
PTEN wild-type GSK2256098 uterine cancer decreased response detail...
PTEN mutant GSK2256098 + Paclitaxel uterine cancer sensitive detail...
PTEN mutant GSK2256098 + Topotecan uterine cancer sensitive detail...
PIK3CA I391M Sirolimus uterine cancer predicted - sensitive detail...
FGFR2 amp Debio 1347 uterine cancer predicted - sensitive detail...
PIK3CA mutant Copanlisib uterine cancer predicted - sensitive detail...
CD274 positive Atezolizumab uterine cancer predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02349958 Phase II Mitomycin C Cisplatin Doxorubicin Clinical Trial of Intraperitoneal Hyperthermic Chemotherapy Unknown status USA 0
NCT02584478 Phase Ib/II Anlotinib + Carboplatin + Paclitaxel Phase 1/2a Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) Recruiting USA | ITA | ESP 2
NCT02646319 Phase I Nab-rapamycin Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations Completed USA 0
NCT02725489 Phase II Durvalumab + FANG vaccine Pilot Study of Durvalumab and Vigil in Advanced Women's Cancers Completed USA 0
NCT02874430 Phase II Doxycycline + Metformin Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer Active, not recruiting USA 0
NCT03206177 Phase I Carboplatin + Galunisertib + Paclitaxel Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or Ovary Active, not recruiting USA 0
NCT03241745 Phase II Nivolumab A Study of Nivolumab in Selected Uterine Cancer Patients Active, not recruiting USA 0
NCT03454451 Phase I CPI-006 CPI-006 + Pembrolizumab CPI-006 + CPI-444 CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers Active, not recruiting USA 1
NCT04250597 Phase I GNX102 Study of GNX102 in Patients With Advanced Solid Tumors Recruiting USA 0
NCT04424641 Phase Ib/II GEN1044 A Study on the Safety of GEN1044 (DuoBody-CD3x5T4) in Subjects With Malignant Solid Tumors Terminated USA | ESP 2
NCT04493619 Phase Ib/II Carboplatin + PLX2853 PLX2853 PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer Terminated USA | CAN 0
NCT04682431 Phase I Pembrolizumab + PY159 PY159 A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors Recruiting USA 0
NCT05180474 Phase Ib/II GEN1047 Research Trial to Study Safety of GEN1047 (DuoBody-CD3xB7H4) in Participants With Malignant Solid Tumors Recruiting FRA | ESP 1
NCT05394675 Phase I DS-9606a A Study of DS-9606a in Patients With Advanced Solid Tumors Recruiting USA 1
NCT05607498 Phase I EMB-07 First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors Not yet recruiting 2