Disease Detail

ID DOID:3963
Name thyroid carcinoma
Definition A thyroid cancer that has_material_basis_in epithelial cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer endocrine gland cancer thyroid cancer thyroid carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Vandetanib thyroid carcinoma not applicable detail...
RET C634W Sorafenib thyroid carcinoma sensitive detail...
RET C634W Ponatinib thyroid carcinoma sensitive detail...
RET M918T Ponatinib thyroid carcinoma sensitive detail...
RET C634W Cabozantinib thyroid carcinoma sensitive detail...
Unknown unknown Obatoclax thyroid carcinoma not applicable detail...
Unknown unknown Sorafenib thyroid carcinoma not applicable detail...
Unknown unknown MLN8054 thyroid carcinoma not applicable detail...
BRAF V600E PIK3CA H1047R Dabrafenib + Everolimus + Trametinib thyroid carcinoma predicted - sensitive detail...
BRAF V600E PIK3CA H1047R Everolimus thyroid carcinoma resistant detail...
BRAF V600E PIK3CA H1047R Dabrafenib + Trametinib thyroid carcinoma resistant detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01208051 Phase Ib/II Cediranib + Lenalidomide Cediranib Cediranib Maleate With or Without Lenalidomide in Treating Patients With Thyroid Cancer Active, not recruiting
NCT01655719 Phase II Pioglitazone Pioglitazone in Thyroid Cancers Completed
NCT02428712 Phase Ib/II PLX8394 A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors Active, not recruiting
NCT02628067 Phase II Pembrolizumab Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) Recruiting
NCT02834013 Phase 0 Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting
NCT03181100 Phase II Nab-paclitaxel Paclitaxel Atezolizumab + Cobimetinib Atezolizumab + Bevacizumab Atezolizumab + Nab-paclitaxel Atezolizumab + Cobimetinib + Vemurafenib Atezolizumab + Paclitaxel Atezolizumab Combinations With Chemotherapy for Anaplastic and Poorly Differentiated Thyroid Carcinomas Recruiting