Disease Detail

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ID DOID:4845
Name pilomyxoid astrocytoma
Definition A pilocytic astrocytoma that is characterized by a monomorphic architectural pattern, usually associated with the absence of Rosenthal fibers and eosinophilic granular bodies.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation benign neoplasm cell type benign neoplasm low grade glioma childhood low-grade glioma pilocytic astrocytoma pilomyxoid astrocytoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
FGFR1 V592M FGFR1 K687E Debio 1347 pilomyxoid astrocytoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01837862 Phase Ib/II Carboplatin + Mebendazole + Temozolomide + Vincristine Sulfate Bevacizumab + Irinotecan + Mebendazole A Phase I/II Study of Mebendazole for the Treatment of Pediatric Gliomas Recruiting USA 0
NCT04923126 Phase Ib/II PD-0325901 SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma Recruiting USA 0
NCT05956821 Phase Ib/II Bevacizumab + Cetuximab Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age Recruiting USA 0