Disease Detail


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ID DOID:5078
Name ganglioglioma
Definition A cell type benign neoplasm that has_material_basis_in glial-type cells.
Source DiseaseOntology.org
Alt Ids DOID:5607 DOID:5606
Path disease disease of cellular proliferation benign neoplasm cell type benign neoplasm ganglioglioma


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
BRAF V600E Dabrafenib ganglioglioma predicted - sensitive detail...
BRAF L514V BRAF V600E Dabrafenib ganglioglioma resistant detail...
BRAF V600X Dabrafenib ganglioglioma predicted - sensitive detail...
BRAF V600E Dabrafenib + Trametinib ganglioglioma sensitive detail...
BRAF V600E Cobimetinib + Vemurafenib ganglioglioma sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01999270 Phase I Bevacizumab + Irinotecan Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors Completed
NCT03919071 Phase II Dabrafenib + Trametinib Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma Recruiting
NCT03975829 FDA approved Dabrafenib + Trametinib Pediatric Long-Term Follow-up and Rollover Study Recruiting