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JSI-1187 is a small molecule inhibitor of Erk1/2 that also results in decreased phosphorylation of Rsk1, and may lead to inhibition of cell proliferation and tumor growth inhibition (Cancer Res 2020;80(16 Suppl):Abstract nr 4188).
|DrugClasses||ERK Inhibitor (pan) 17|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Dabrafenib + JSI-1187||Dabrafenib JSI-1187||1||1|