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Drug Name JSI-1187
Trade Name
Synonyms JSI-1187-01|JSI1187|JSI 1187
Drug Descriptions

JSI-1187 is a small molecule inhibitor of Erk1/2 that also results in decreased phosphorylation of Rsk1, and may lead to inhibition of cell proliferation and tumor growth inhibition (Cancer Res 2020;80(16 Suppl):Abstract nr 4188).

DrugClasses ERK Inhibitor (pan) 18
CAS Registry Number NA
NCIT ID C174203


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Dabrafenib + JSI-1187 Dabrafenib JSI-1187 1 1
JSI-1187 JSI-1187 2 1
JSI-1187 + Sotorasib JSI-1187 Sotorasib 0 0

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